Aerosolised antipsychotic assuages agitation: inhaled loxapine for agitation associated with schizophrenia or bipolar disorder
نویسندگان
چکیده
منابع مشابه
Inhaled loxapine for rapid treatment of agitation in schizophrenia and bipolar disorder: an update
253 ISSN 1758-2008 10.2217/NPY.12.23 © 2012 Future Medicine Ltd Neuropsychiatry (2012) 2(3), 253–260 Summary Agitation is a common presenting problem in emergency departments and treatments currently range from de-escalation techniques to medications, in either oral or intramuscular forms. Oral medications can be diverted and have a relatively long delay of onset. This delay is problematic for ...
متن کاملInhaled Loxapine for Psychotic Agitation
Preliminary research has demonstrated rapid and robust positive effects of ketamine (Ketalar) infusion on depressive symptoms, but controlled trials are needed to confirm the clinical efficacy as well as to establish optimal dosing. Safety of repeated ketamine infusions, while theoretically plausible, has not been systematically established. In addition, the level of physiological monitoring ne...
متن کاملInhaled Loxapine for Agitation in Intoxicated Patients: A Case Series
OBJECTIVES Episodes of agitation are frequent in intoxicated patients who have a substance use disorder, a psychiatric disorder or both (dual diagnosis). For managing the agitation, it is necessary to act promptly in a safe environment and addressing any underlying etiology. Inhaled loxapine improves symptoms of agitation in adults with psychiatric disorders (eg, schizophrenia) within 10 minute...
متن کامل[Inhaled loxapine: A novel treatment for agitation in psychotic disorders].
Psychomotor agitation is a widespread clinical problem both in patients with schizophrenia and BD. It is a highly hazardous condition, imposing significant risks in psychiatric emergency, as expressedby elevated ratios of adverse events and traumatic experiences (both for patients and medical staff). The available anti-agitation drugs have numerous disadvantages. The orally administered medicat...
متن کاملResponse to inhaled loxapine in patients with schizophrenia or bipolar I disorder: PANSS-EC responder analyses
Background Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale - Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated patients with schizophrenia and 314 patients with bipolar I disorder (Clinicaltrials.gov: NCT00628589, NCT00721955). Aims To examine the five individ...
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ژورنال
عنوان ژورنال: International Journal of Clinical Practice
سال: 2010
ISSN: 1368-5031
DOI: 10.1111/j.1742-1241.2010.02615.x